Also inform your healthcare provider about any medical conditions, supplements, and over-the-counter meds you are taking. For chronic obstructive pulmonary disease (COPD), the recommended dosage of Trelegy is one inhalation (puff) of Trelegy Ellipta 100/62.5/25 mcg once each day. The Fluticasone furoate is not the same as fluticasone propionate. This is safe for use in the lungs, all milled to an incredibly fine powder that the Other treatment options include long-acting muscarinic antagonists or anticholinergics, such as Spiriva (tiotropium), leukotriene modifiers, such as Singular (montelukast), and biologics, such as Xolair (omalizumab). <>/ExtGState<>/Font<>/ProcSet[/PDF/Text/ImageB/ImageC/ImageI] >>/Annots[ 33 0 R 36 0 R] /MediaBox[ 0 0 540 720] /Contents 4 0 R/Group<>/Tabs/S/StructParents 0>> Advair (fluticasone / salmeterol) Makes it easier to breathe. Purchasing medication online can be a stressful experience especially if its the first time. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). Generic Advair's price at certain pharmacies is less than $75 with a free GoodRx discount. Med Lett Drugs Ther. Our representatives can answer any of your questions, connect you with the on-call pharmacist, or help you place your order. Strong growth of vaccine and respiratory portfolio boosts sales. Lets get further into what sets Trelegy apart from the rest of the pack. , such as Singular (montelukast), and biologics, such as Xolair (omalizumab). will not work unless they are used properly. Similar to Symbicort, Breo is indicated for the long-term treatment of asthma and COPD. Policy. budesonide, glycopyrrolate, and formoterol fumarate, fluticasone furoate/umeclidinium bromide/vilanterol trifenatate. another product that combines an inhaled corticosteroid (fluticasone furoate) and long acting In most cases, a healthcare provider may recommend healthy lifestyle changes on top of medication. Similar to Symbicort, Breo is indicated for the long-term treatment of asthma and COPD. Lupron Eligard . Before you switch to a new medication, make sure its covered by your insurance plan. What Makes Trelegy Better Than Other Inhalers? I was tasked with comparing Advair, Breo and Trelegy. Trelegy is not a fast-acting medication and will not replace a rescue inhaler for sudden breathing problems. Expanded table: Correct use of inhalers for asthma. Advair and Symbicort belong to the same drug class, but Advair contains different active ingredients (fluticasone/salmeterol). Beta2-adrenergic agonists also known as adrenergic 2 receptor agonists are a class of drugs that act on the 2 adrenergic receptor. The .gov means its official. is also common in COPD patients, and supplementation may help ease COPD symptoms. Call your doctor right away if you have serious side effects such as lung infections, high blood pressure, cataracts, or decreased bone density. . Trelegy is a triple therapy medication approved to treat COPD. Bookshelf Trelegy is the first FDA-approved triple therapy for the maintenance treatment of asthma and COPD. Breztri aerosphere will significantly reduce the annual rate of moderate or severeCOPD exacerbations. While many different inhaler medications are available, the following are the most common alternatives to Symbicort. with the actuation of an aerosol inhaler (the aerosol dissipates quicklythe Products that combine long-acting beta2-agonists (B2-agonists) and inhaled corticosteroids relax airway muscles, making airways wider and making it easier to breathe. often contain milk proteins, which can be a problem for someone who is lactose intolerant. Trelegy Ellipta is not indicated for the relief of acute bronchospasm or for the treatment of asthma. Looking for relief for a scratchy, dry throat? It comes in two forms: Advair Diskus and Advair HFA. Fast-acting inhalers typically contain some sort of bronchodilator. Continue reading to learn more about Advair Diskus alternatives and how they compare. Breztri Aerosphere vs. Trelegy Ellipta. Some supplements and herbal medicines may interact with other, If youre considering switching to an alternative, you should always seek. Additionally, the medication is not indicated for use in children, as its safety and efficacy in this population has not been established. NorthWestPharmacy.com Inc. Tenemos servicio en Espaol esta disponible de Lunes a Viernes desde las 8:00am hasta las 4:00pm, Tiempo del Pacfico. Rocklatan costs $389 without insurance. Theyve probably tried more than one medication in their quest to find the one that works best for them. Some people may also prefer Trelegy because of its. Pharmaceutical companies are allowed to set the price wherever they want in the U.S. It can also cause serious side effects including lung infection and a weakened immune system. Umeclidinium is the second active ingredient the one that sets it apart from Breo Ellipta. Por favor, llamenos gratis al 1-866-539-5330. . Med Lett Drugs Ther. This once-daily dosing schedule may be preferable for certain patients. of drug, and can be expected to act similarly to one another. RELATED: 7 home remedies for asthmaand what to do if they dont work. including lung infection and a weakened immune system. delivered using a dry-powder inhaler (DPI). Unfortunately, being both new and effective makes it one of the most expensive treatment options. The Phase 3 IMPACT study compared Trelegy to other common COPD medications in 10,355 patients in 37 countries, according to GlaxoSmithKline (GSK) and Innoviva.. People who have trouble forgetting to take their second dose of Advair Diskus may find the dosing schedule of Breo Ellipta more convenient. Worth H, Buhl R, Crie CP, Kardos P, Lossi NS, Vogelmeier CF. Manufactured by AstraZeneca, Symbicort contains a combination of two active ingredients: budesonide and formoterol. Fluticasone propionate reduces the swelling and irritation that can lead to complications, such as an asthma attack. One thing to keep in mind is that, is approved to treat asthma in people aged, approved to treat COPD. While fast-acting inhalers are still recommended in the event of an emergency, a significant portion of the population responds positively to long-term treatments referred to as inhaled corticosteroids. However, more studies are needed to understand the full effect of yoga in asthma management. Generic Symbicort's price at certain pharmacies is less than $100 with a free GoodRx discount. Its undoubtedly frustrating for people who need medications like Trelegy to see such high prices. Drug companies are constantly trying to come up with more effective ways to treat various diseases. If you prefer, you can order online yourself, or email us well get back to you as soon as possible. Fluticasone propionate is a common corticosteroid, also known simply as a steroid. This is why fast-acting inhalers are still recommended, even for people who have their asthma or COPD under control with an inhaled corticosteroid. Each countrys government is inclined to find a fair compromise for the pharmaceutical company. These ingredients work together to make it easier to breathe. Cash price around 500 dollars. Natural or non-medication alternatives to, may be useful for improving and controlling symptoms of asthma or COPD. low blood potassium level. In the United States, the cash price for a one-month supply of Trelegy Ellipta is about $665.00. Wixela Inhub, Advair HFA, Breo Ellipta, Anoro Ellipta, and Trelegy are some Advair Diskus alternatives. pneumonia (a kind of lung infection) problems with adrenal gland function. We maintain the highest standards through certification from not one, but two highly acclaimed independent professional organizations: the Canadian International Pharmacy Association (CIPA) and the International Pharmacy Association of British Columbia (IPABC). In a clinical study comparing the effects of Breo versus Symbicort in asthma patients, both drugs showed similar improvements in lung function. than Symbicort. Breo has been approved for adults 18 years and older, while Advair has been approved for both adults and children 4 years and older. Advair HFA is an aerosol metered-dose inhaler only approved for asthma, while Advair Diskus is a dry powder inhaler approved for both asthma and COPD. Unauthorized use of these marks is strictly prohibited. However, these products are comprised of active If fluticasone furoate is truly more effective for some people, then having affordable access to it is critical. There are numerous alternatives to Advair Diskus available on the market. 100/25, as well as 200/50. Because Advair and Symbicort are both ICS/LABA combination medications, they have similar side effects such as upper respiratory infection, headache, sinus pain, and oral thrush. Salmeterol is a bronchodilator, which means that it helps open up the airways. Natural remedies can help patients with asthma and COPD manage their daily symptoms and improve quality of life. and its alternatives should only be used as a, for asthma or COPD. Long-acting beta-2 agonists are not used as rescue inhalers for acute symptoms of asthma or COPD. Advair Diskus (fluticasone and salmeterol oral inhaler) is a combination of a corticosteroid and a beta2-adrenergic bronchodilator used to treat asthma and chronic bronchitis, including COPD associated with chronic bronchitis. Budesonide belongs to a class of drugs called inhaled corticosteroids (ICS), which reduce inflammation in the lungs. However, Anoro Ellipta can be dosed once daily. having to spend hours tied to a nebulizer. Dosing becomes a simple An official website of the United States government. Ulrik CS. Clipboard, Search History, and several other advanced features are temporarily unavailable. Asthma and COPD flare-ups result in the restriction of the airway, making it difficult for the patient to breathe. Disclaimer. In these situations, a healthcare provider may suggest a different medication or natural alternatives to disease management. In these situations, a healthcare provider may suggest a different medication or natural alternatives to disease management. }LX? Pharmacy names, logos, brands, and other trademarks are the property of their respective owners. user doesn't even perceive while inhaling it. Natural or non-medication alternatives to Advair Diskus may be useful for improving and controlling symptoms of asthma or COPD. 2018 May 21;60(1547):86-88. Perforomist, Serevent Diskus, Striverdi Respimat, Incruse Ellipta, and Advair Diskus are some Brovana alternatives. weakened immune system *. Save with GoodRx. Advair (fluticasone / salmeterol) combines two medicines into one inhaler, but it might be expensive. Advair is available as two dosage forms: Advair Diskus and Advair HFA. Contact your insurance company or pharmacist to find out the cost of your different treatment options. . If you are switching to a, correctly in order to get the most benefit. They both work by relaxing the muscles around the airways. Unlike Advair Diskus, however, Advair HFA is only approved for the treatment of asthma. Why are Eliquis and Xarelto So Expensive? Fluticasone in combination with Salmeterol (bonchodilator) Advair Diskus 100/50 Advair Diskus 250/50 Advair Diskus 500/50. I have tried Loryna twice and both times I have broken out into hives. In most cases, a, may recommend healthy lifestyle changes on top of medication. As an FDA-approved generic of ADVAIR DISKUS , you can expect Wixela Inhub to be just as . Advair (fluticasone / salmeterol) combines two medicines into one inhaler, but it might . Led development of Global strategic marketing tactics for two TRELEGY global multi-channel campaigns . Breztri aerosphere is available as an inhalation aerosol, in the following doses: Pressurized metered-dose inhaler containing a combination of budesonide (160 mcg), glycopyrrolate (9 mcg), and formoterol fumarate (4.8 mcg) per inhalation. Advair HFA 45/21 Advair HFA 115/21 Advair . 2 puffs of 80-160 mcg/4.5 mcg twice daily, 2 puffs twice daily (strength depends on severity), Breztri Aerosphere (budesonide / glycopyrrolate / formoterol), 2 puffs of 160 mcg/9 mcg/4.8 mcg twice daily, Sinusitis, throat irritation, upper respiratory infection, Nasopharyngitis, nausea, nasal congestion, Dry mouth, sinusitis, upper respiratory infection, Trelegy Ellipta (fluticasone / umeclidinium / vilanterol), 1 puff of 100-200 mcg/62.5 mcg/25 mcg once daily, Airduo RespiClick (fluticasone/salmeterol), . Not to mention we all Our record is stellar. Advair HFA 230mcg/21mcg . I thought i would reach out to a pharmacist! Dulera contains the steroid mometasone and the LABA formoterol. are different active ingredients from those in Advair, they are the same type 2020 Dec 14;62(1613):e204-e208. Trelegy Ellipta--a three-drug inhaler for COPD. Estamos trabajando para solucionar este problema y por el momento deberan usar los siguientes numeros: But dont take our word for it look through the 400,000+ internet pharmacy reviews our satisfied customers have written using third-party websites like Trustpilot, Norton, and Shopper Approved. {:28D8 {83 <3kRET__.0ZLr? This means it activates a specific type of It contains an anticholinergic called umeclidinium and a, . official website and that any information you provide is encrypted It contains a combination of, furoate, an ICS, umeclidinium, an anticholinergic, and, may recommend an alternative like Trelegy. Trelegy Ellipta is a combination of 3 different classes of medication. 3 0 obj Umeclidinium is classified as an anticholinergic, which means that it relaxes and opens airways in the lungs. A quick look through the customer feedback on our website will show you that our customers are from every state and just about every city in the country. We do not endorse non-Cleveland Clinic products or services. Common side effects of Trelegy include respiratory infection, sore throat, sinusitis, and oral thrush. Treatment for this kind of asthma usually includes prescription medicines, such as inhalers, but lifestyle changes can also help, Both conditions involve how your body makes and uses insulinheres how to tell them apart, A diet high in protein, whole grains, and greens helps stabilize blood sugar. Instead, a healthcare provider will prescribe a short-acting beta agonist, such as ProAir (albuterol) or Ventolin (albuterol), for immediate relief of a COPD or asthma attack. working in concert makes for a magical level of efficiency in preventing or The https:// ensures that you are connecting to the to the drug, which can unfortunately cause issues at times. Duaklir Pressair: another LAMA/LABA inhaler for COPD. is umeclidinium, which is in a class of drugs used for COPD but not asthma They do not replace short acting inhalers like albuterol. capabilities, the easier it becomes to coordinate. Keywords: <> I just started Trelegy For COPD. HHS Vulnerability Disclosure, Help possible. However, some patients may find the Advair Diskus inhaler easier to use because it requires less hand-breath coordination than Symbicort. Change in the color of your snot may indicate that something is going on - learn what colors to look for and when to consult your healthcare provider, Patients with breathing problems may require treatment with the brand-name medication Symbicort. These include: Trelegy Ellipta can interact with other medications. Bronchodilators relax the muscles around the airways so they can remain open. This stimulates the receptors, making the cells produce less of the substances that trigger inflammation and more of the substances that reduce inflammation. Trelegy is the first FDA-approved triple therapy for the maintenance treatment of asthma and COPD. I have lorazepam by two different companies. However, some patients may find the Advair Diskus inhaler easier to use because it requires less. The pharmacist does not know, saying maybe she thought this was good strenght for me. Another popular dual-medication is Symbicort, which is comprised of the same types of medications, but different active ingredients. <> Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Symbicort (budesonide/formoterol), Breo (fluticasone/vilanterol), and Dulera (mometasone/formoterol) are similar inhalers to Advair Diskus that contain an ICS and LABA combination. 2023 SingleCare Administrators. 2020 Dec 14;62(1613):e200-e203. As a reminder, inhaled corticosteroids are not meant to be used as fast-acting inhalers. immune system in that area and allow yeasts to colonize and grow. National Library of Medicine Mild exacerbations are treated with short acting bronchodilators (SABDs). that contains milk proteins, which may not be suitable for someone with a severe milk allergy. powder just sits tight until the patient breathes in. We wont get into the scientific details here (click on the link and read the paper if youre interested), but the important thing is for this article is that its similar but not the same. Compared to Symbicort, Trelegy was shown to reduce COPD exacerbations by 35% more. If youre ready to order Trelegy (or any other medication you need), dont hesitate to call us at 1-866-539-5330. Other factors such as side effects, the type of inhaler device, and disease severity may also influence someone to try a Symbicort alternative. endobj At the very least, it was certainly a great review Once this is set, the pharmaceutical company is bound to it if they want to sell their drugs in the country. Advair Diskus, manufactured by GlaxoSmithKline, is one of the most commonly prescribed inhalers. Other treatment options include long-acting. The list price for a 30-day supply of TRELEGY is $638.52 1, but it's important to remember the list price is not the price you pay. (COPD). drugs. TRELEGY was also shown advair vs trelegy to significantly improve health-related quality of life Trelegy Ellipta fluticasone / umeclidinium / vilanterol. These organizations set standards for online Canadian pharmacies and internet drugstores to ensure safety and accuracy. Salmeterol is part of the class of drugs known as long-acting beta agonists, and Fluticasone is part of a class of drugs known as corticosteroids. lower with Breztri than with Symbicort, and both medications had similar rates of side effects such as pneumonia, upper respiratory infection, and bronchitis. Possible Concerns Do not use these products as rescue inhalers for quick relief. government site. This means it has anti-inflammatory and Last reviewed by a Cleveland Clinic medical professional on 09/14/2018. Expanded table: Some inhaled drugs for treatment of asthma. Compare Advair Diskus alternatives| Wixela Inhub | Advair HFA | Breo Ellipta | Anoro Ellipta | Trelegy | Natural alternatives | How to switch meds. Advertising on our site helps support our mission. FOIA The content on this website is intended for information purposes only. Always contact your healthcare provider if you have questions about your personal situation. Fluticasone is an inhaled corticosteroid (ICS) that helps reduce inflammation in the lungs, while salmeterol is a long-acting beta agonist (LABA) that relaxes the muscles in the lungs and opens up the airways. Purchasing a 3-month supply will probably cost a bit less per inhaler. Bethesda, MD 20894, Web Policies The information on this website should not be relied upon and is not a substitute for professional medical advice. In a. comparing the effects of Breo versus Symbicort in asthma patients, both drugs showed similar improvements in lung function. Trelegy is given at one inhalation once daily. Before taking a supplement or herbal medicine for your condition, its important to consult a, . The third is umeclidinium, which is in a class of drugs used for COPD but not asthma called antimuscurinics. to improve quality of life, reduce asthma symptoms, and reduce medication use in some patients. Patients with breathing problems may require treatment with the brand-name medication Symbicort. Trelegy Ellipta is an orally inhaled medicine that contains three medications in one inhaler. Note: Short-acting beta agonists like albuterol are not alternatives to long-acting beta agonists such as Symbicort. While the name Trelegy may be different, some of the active ingredients should sound familiar. PMC For patients who have not responded well to Advair or Symbicort, Trelegy is a lifeline. GOLD 2017 treatment pathways in 'real life': An analysis of the DACCORD observational study. Treatment for this kind of asthma usually includes prescription medicines, such as inhalers, but lifestyle changes can also help. The https:// ensures that you are connecting to the Anoro Ellipta (umeclidinium / vilanterol) is good first-choice treatment for chronic obstructive pulmonary disease (COPD), but may be more expensive than older medicines that work just like as well. For patients who have not responded well to Advair or Symbicort, Trelegy is a lifeline. local: (604) 539-5330Fax local: (604) 539-5331. One of the most popular dual-medication drugs on the market is Advair. If you have health insurance, the price you pay - sometimes called your out-of-pocket cost - is set by your prescription drug plan. However, dry powder inhalers like Advair Diskus often contain milk proteins, which can be a problem for someone who is lactose intolerant. and transmitted securely. Asthma or COPD that is not optimally controlled by Symbicort may require different or additional medications. Alternative therapies for asthma and COPD include the following treatments, lifestyle modifications, and vitamins: There is less scientific evidence about the effectiveness of these natural alternatives compared to prescription medicines. It might seem Natural remedies can help patients with asthma. I had covid twice. ?QBJ)1$%SrnQz_>!dE`Zf,Q@F+q4;>%T!LB?e'ml8ys}|~=;"rf(;h1~1i:OG)2Led#\4\%9FD}4N;[dIi=]3z,n'ruA7f}V-9_=>jI(\}?OZ3"#I=c3)R| W[|z5c@9v&%uv(~Zs"xWO.8?6A%So_y-`"%Ck5j. The final active ingredient in Trelegy is vilanterol trifenatate, a long-acting beta2 adrenoceptor agonist that is classified as a bronchodilator. Breo is Advair Diskus is given at a dose of one inhalation twice daily and Advair HFA as two inhalations twice daily. As previously mentioned, Trelegy is one of the more expensive medications used to treat COPD and asthma. x\[o~"Z~i ;n&#XRrG7v^K.WNk^>y>#>! . Breztri and Symbicort are both dosed at two inhalations twice daily. Let's look at these three drug Trelegy incorporates fluticasone furoate, umeclidinium (another LAMA), and vilanterol trifenatate in their formula. Med Lett Drugs Ther. Get useful, helpful and relevant health + wellness information, 9500 Euclid Avenue, Cleveland, Ohio 44195 |, Important Updates + Notice of Vendor Data Event, Visitation, mask requirements and COVID-19 information, ipratropium bromide and albuterol sulfate, Combivent is the brand name for albuterol and, Advair is the brand name for a combination of, Symbicort is the brand name for a combination of formoterol (Foradil) and, Dulera is the brand name for a combination of, DuoNeb is the brand name for a combination of, BREO is the brand name for a combination of, Stiolto is the brand name for a combination of, Anoro is the brand name for a combination of, Nervousness, tremor, palpitations, rapid heartbeat, increased blood pressure. If cost is the main concern with finding an alternative to, requires some coordination between pressing down on the canister and inhaling the medicine. hesitate to use us as a resource to help you provide the best patient care The. Using certain, Sometimes making a switch is a matter of finding the most affordable option. of asthma/COPD pharmacotherapy for this author. These standards include keeping proper patient records, having a pharmacist review potential contraindications, and connecting customers to a pharmacist as required. As of December 2022, the following changes have been made: Maximum savings of $500 per month between January 1, 2023 and March 31, 2023; and $200 per month at all other times; Compare examples of other drugs for the long-term treatment of asthma and COPD are listed below. It helps to reduce inflammation and relax your airways and lungs, opening them up and making it easier for you to breathe. Again, like the others, it is important to rinse the mouth after use. Trelegy combines three active ingredients called fluticasone furoate, umeclidinium, and vilanterol. The site is secure. Advair; AirDuo; Anoro Ellipta; Bevespi Aerosphere; Breo Ellipta; Brovana; COPD; Duaklir Genuair; Duaklir Pressair; Incruse Ellipta; Inspiolto Respimat; Lonhala Magnair; Perforomist; Serevent; Spiriva Handihaler; Spiriva Respimat; Stiolto Respimat; Striverdi Respimat; Symbicort; Trelegy Ellipta; Tudorza Genuair; Tudorza Pressair; Wixela Inhub; Yupelri; aclidinium; adverse effects; arformoterol; budesonide/formoterol; dosage; drug interactions; efficacy; fluticasone furoate; fluticasone propionate; fluticasone/vilanterol; formoterol; glycopyrrolate; glycopyrronium; long-acting beta2-agonists; olodaterol; revefenacin; safety; salmeterol; tiotropium; tiotropium/olodaterol; umeclidinium; umeclidinium/vilanterol; vilanterol. We look forward to helping you save you money! Med Lett Drugs Ther. Breztri Aerosphere can improve lung function and reduce the number of COPD flare-ups you have. Just like Advair, it is recommended to rinse the mouth out after use to prevent thrush infections. I'm a nursing student in my first year in pharmacology. FOIA They should not be used as rescue inhalers for COPD exacerbations or for asthma attacks. Fluticasone Propionate/Salmeterol (ADVAIR/GENERICS) Fluticasone Furoate/Vilanterol (BREO ELLIPTA 100/25 only ) . From day one, our staff, pharmacists, and knowledgeable representatives have been dedicated to low prices, patient safety and excellent customer service. Breathing exercises practiced in yoga have been. Advair Diskus & Advair HFA . F>4spm+4%*9\~=;U L@Ozs$RBa2FS1(opE,u lk9+D6PL9"g>,U\xfY$J=#>y So, can yuo compare these three drugs? allergic reaction . These alternatives also come in both generic and brand-name forms. Talk to your physician or pharmacist if you have any concerns about side effects. If treatment with Advair Diskus is not improving symptoms of COPD, a healthcare provider may recommend an alternative like Trelegy. examining the role of vitamin D in asthma treatment, vitamin D intake reduced the risk of having an asthma attack requiring hospitalization. It's vilanterol that allows Trelegy (and Breo) to be a once-daily medication as opposed to twice. Both these inhalers are known as combination inhalers: They contain a corticosteroid (to improve inflammation in the airway) and a beta-2 agonist (to keep the airways relaxed and open). Facing the prospect of generic competition to respiratory superstar Advairand as. One is from Leading Pharmaceuticals and the other is Valeant Pharmaceuticals. It is a combination of budesonide, an inhaled corticosteroid (ICS), glycopyrrolate, a long-acting anticholinergic (sometimes called a long-acting muscarinic antagonist (LAMA)), and formoterol fumarate, a long-acting beta2-agonist ((LABA) bronchodilator), indicated for the maintenance treatment of COPD (chronic obstructive pulmonary disease). Most Americans know by now that they pay more for their prescription drugs than people in other countries. Cleveland Clinic is a non-profit academic medical center. Trelegy is a triple therapy medication approved to treat COPD. In addition, some studies suggest that ginseng can help improve lung function. to get his/her medication. Treatment options for COPD and asthma have come a long way in the past 30 years. Because Advair and Symbicort are both ICS/LABA combination medications, they have similar side effects such as upper respiratory infection, headache, sinus pain, and oral thrush. All three are Everything You Need to Know, How to Get the Best Prices on Your Prescription Medication. Patients should always carry a rescue inhaler with them in case of an emergency. I am . information, and even trivia about drugs, and we love to talk about them. treatment of chronic obstructive pulmonary disease, Maintenance treatment of patients with chronic obstructive pulmonary disease (COPD), Treatment of chronic obstructive pulmonary disease (COPD), Upper respiratory tract infection, pneumonia, Glaucoma and cataracts, worsening of narrow-angle glaucoma, Increased blood pressure, a fast or irregular heartbeat, chest pain, Fungal infections (candida/thrush) in your mouth and throat, Severe allergic reactions rashes, itching, swelling in your face, tongue, and throat, and difficulties breathing, Increased risk of developing pneumonia if you have COPD, A sudden worsening of your asthma symptoms, including asthma attacks, Eye problems, including glaucoma, cataracts, and blurred vision, HIV protease inhibitors atazanavir, indinavir, ritonavir, saquinavir, Immunosuppressants fingolimod, ozanimod, siponimod, Antibiotics clarithromycin, telithromycin, Antiarrhythmics amiodarone, dronedarone, Diuretics bendroflumethiazide bumetanide, furosemide, Antidepressants citalopram, fluoxetine, sertraline, venlafaxine, Calcium channel blockers amlodipine, felodipine, nifedipine, diltiazem, verapamil, Anticonvulsants carbamazepine, phenobarbital, phenytoin, Corticosteroids betamethasone, cortisone, prednisolone, Beta-blockers labetalol, propranolol, sotalol, Treatments for an irregular heartbeat amiodarone, dronedarone, disopyramide, Diuretics bendroflumethiazide, furosemide, Antidepressants citalopram, escitalopram, fluoxetine, sertraline, Tricyclic antidepressants clomipramine, desipramine, imipramine, Immunosuppressants fingolimod, siponimod, Corticosteroids betamethasone, cortisone, dexamethasone, prednisolone, Are allergic to the active ingredient budesonide, glycopyrrolate, or formoterol fumarate, Have had an allergic reaction to any of the other ingredients in Breztri aerosphere, Are taking any of the medications that could interact with Breztri aerosphere, Have heart problems orhigh blood pressure, Have eye problems such as glaucoma or cataracts, Have prostate or bladder problems, or problems passing urine, Have a viral, bacterial, parasitic, or fungal infection, Are pregnant or are planning to become pregnant, Are breastfeeding or are planning to breastfeed, Are allergic to the active ingredient fluticasone furoate, umeclidinium, or vilanterol, Are allergic to any of the other ingredients in Trelegy Ellipta, Are taking long-acting beta-agonists (LABA) or an anticholinergic, Have any problems with your immune system, Have any eye problems, including cataracts or glaucoma, Have or have ever had any problems with your adrenal glands, Have recently been around someone who has measles or chickenpox, Have a mild to moderate milk protein allergy, Have any prostate or bladder problems, or problems passing urine, Potential worsening of infections such as existing tuberculosis, fungal, bacterial, viral, or parasitic infections, ocular herpes simplex, Hypokalemia low levels of potassium may cause symptoms of muscle spasm, muscle weakness, or abnormal heart rhythm, Effects on your heart increased blood pressure, a fast or irregular heartbeat, chest pain, Fungal infections (candida/thrush) in your mouth and throat this is less likely if you rinse your mouth out with water after taking your Trelegy Ellipta, Increase in upper respiratory tract infections, like the common cold, the flu, and sinus infections, Life-threatening allergic reactions including rashes, itching, swelling in your face, tongue, and throat, chest pain, and shortness of breath, An increased risk of developing pneumonia if you also have chronic obstructive pulmonary disease (COPD), Sudden worsening of your asthma symptoms, including asthma attacks (paradoxical bronchospasm), An increased risk of eye problems, including glaucoma, cataracts, and blurred vision, Strong cytochrome P450 3A4 inhibitors ketoconazole, ritonavir, atazanavir, clarithromycin, indinavir, itraconazole, Monoamine oxidase inhibitors and tricyclic antidepressants, Anticholinergic tiotropium, ipratropium, or aclidinium, Long-acting beta agonists (LABA) salmeterol, formoterol, arformoterol, olodaterol, or indacaterol, Any medications taken to treat bacterial, viral, or fungal infections, including an HIV infection, such as ketoconazole, itraconazole, ritonavir, nelfinavir, or cobicistat, Are taking another medication that contains long-acting beta-agonists (LABA) or an anticholinergic active ingredient.